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Article

RACK-1 regulates let-7 microRNA expression and terminal cell differentiation in Caenorhabditis elegans.

Cell cycle (Georgetown, Tex.) - 1 Jan 2014

Chu Yu-De, Wang Wei-Chieh, Chen Shi-An A, Hsu Yen-Ting, Yeh Meng-Wei, Slack Frank J, Chan Shih-Peng

Abstract excerpt

The let-7 microRNA (miRNA) regulates cell cycle exit and terminal differentiation in the C. elegans heterochronic gene pathway. Low expression of let-7 results in retarded vulva and hypodermal cell development in C. elegans and has been associated with several human cancers. Previously, the versatile scaffold protein receptor for activated C kinase 1 (RACK1) was proposed to facilitate recruitment of the...

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Identifiers

PMID: 24776851
DOI: 10.4161/cc.29017
PMCID: PMC4111763

Genes

RACK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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RACK-1 regulates let-7 microRNA expression and terminal cell differentiation in Caenorhabditis elegans.PMID 24776851Read ↗

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