Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Two MicroRNAs Are Sufficient for Embryonic Patterning in C. elegans

30 Oct 2020

Abstract excerpt

MicroRNAs (miRNAs) are a class of post-transcriptional repressors with diverse roles in animal development and physiology [1]. The Microprocessor complex, composed of Drosha and Pasha/DGCR8, is necessary for the biogenesis of all canonical miRNAs and essential for the early stages of animal embryogenesis [2-8]. However, the cause for this requirement is largely unknown. Animals often express hundreds of miRNAs,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetics, Aging, and Longevity in Model Organisms
Share to MicroRNA in disease regulation
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33125867
DOI: 10.1016/j.cub.2020.09.066

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Two MicroRNAs Are Sufficient for Embryonic Patterning in C. elegansPMID 33125867Read ↗

Processing of primary microRNAs by the Microprocessor complex.Semantic proximity Read ↗

A noncanonical Pol III-dependent, Microprocessor-independent biogenesis pathway generates a germline enriched miRNA familySemantic proximity Read ↗

Recent Molecular Genetic Explorations of Caenorhabditis elegans MicroRNAs.Semantic proximity Read ↗

Most Caenorhabditis elegans microRNAs are individually not essential for development or viability.Semantic proximity Read ↗

Functional genomic analysis of the let-7 regulatory network in Caenorhabditis elegans.Semantic proximity Read ↗

Optimal male fertility and fecundity in Caenorhabditis elegans require Microprocessor and Argonaute gene function.Semantic proximity Read ↗

The microRNA pathway controls germ cell proliferation and differentiation in C. elegans.Semantic proximity Read ↗

RACK-1 regulates let-7 microRNA expression and terminal cell differentiation in Caenorhabditis elegans.Semantic proximity Read ↗

An overview of the identification, detection, and functional analysis of Drosophila microRNAs.Semantic proximity Read ↗

Misexpression of the Caenorhabditis elegans miRNA let-7 is sufficient to drive developmental programs.Semantic proximity Read ↗

let-756, a C. elegans fgf essential for worm developmentSemantic proximity Read ↗

A Network of Chromatin Factors Is Regulating the Transition to Postembryonic Development in Caenorhabditis elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.