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Article

Genetic variations in STK11, PRKAA1, and TSC1 associated with prognosis for patients with colorectal cancer.

Annals of surgical oncology - 1 Dec 2014

Lee Soo Jung, Kang Byung Woog, Chae Yee Soo, Kim Hye Jin, Park Su Yeon, Park Jun Seok, Choi Gyu Seog, Jeon Hyo-Sung, Lee Won Kee, Kim Jong Gwang

Abstract excerpt

BACKGROUND: Assuming an association between cancer and metabolism, oncogene-directed metabolic reprogramming in cancer has revealed new target strategies. For example, the LKB1-AMPK-mTOR signaling pathway genes are already known to alter the cell metabolism and to play a critical role in the malignant behavior of cancer. Accordingly, based on the assumption that genetic variations in the LKB1-AMPK-mTOR signaling...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24770722
DOI: 10.1245/s10434-014-3729-z

Genes

PRKAA1
STK11
TSC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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