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Article

Genetic variants and animal models in SNCA and Parkinson disease.

Ageing research reviews - 1 May 2014

Deng Hao, Yuan Lamei

Abstract excerpt

Parkinson disease (PD; MIM 168600) is the second most common progressive neurodegenerative disorder characterized by a variety of motor and non-motor features. To date, at least 20 loci and 15 disease-causing genes for parkinsonism have been identified. Among them, the α-synuclein (SNCA) gene was associated with PARK1/PARK4. Point mutations, duplications and triplications in the SNCA gene cause a rare dominant...

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Identifiers

PMID: 24768741
DOI: 10.1016/j.arr.2014.04.002

Genes

SNCA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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