Article
Genes associated with Parkinson syndrome.
Journal of neurology - 1 Sept 2008
Biskup Saskia, Gerlach Manfred, Kupsch Andreas, Reichmann Heinz, Riederer Peter, Vieregge Peter, Wüllner Ullrich, Gasser Thomas
Abstract excerpt
Genetic findings have changed our views on Parkinson's disease (PD) and parkinsonism, which will be collectively referred to as Parkinsonian Syndrome (PS) in the present manuscript. Mutations in several genes are found to cause monogenic forms of the disorder. Point mutations, duplications and triplications in the alpha-synuclein gene cause a rare dominant form of PS in families. Mutations in the leucine-rich...
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