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Article

α-Synuclein and Parkinsonism: Updates and Future Perspectives.

Current neurology and neuroscience reports - 1 Apr 2017

Rosborough Kaie, Patel Neha, Kalia Lorraine V

Abstract excerpt

Mutations in the SNCA gene, which encodes the α-synuclein protein, were the first discovered genetic causes of familial parkinsonism with Lewy pathology. To date, six different SNCA missense mutations as well as multiplications are known to cause parkinsonism. For this review, we performed a literature search to identify all published cases of SNCA-related parkinsonism to provide an updated summary of the...

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Source

Identifiers

PMID: 28324300
DOI: 10.1007/s11910-017-0737-y

Genes

SNCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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