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Article

Pathogenic mutations in Parkinson disease.

Human mutation - 1 Jul 2007

Tan Eng-King, Skipper Lisa M

Abstract excerpt

Parkinson disease (PD; Parkinson's) is the second most common neurodegenerative disease, characterized by the progressive loss of dopamine neurons and the accumulation of Lewy bodies. Increasing evidence suggests that deficits in mitochondrial function, oxidative and nitrosative stress, the accumulation of aberrant or misfolded proteins, and ubiquitin-proteasome system (UPS) dysfunction may represent the...

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Source

Identifiers

PMID: 17385668
DOI: 10.1002/humu.20507

Genes

PARK7
PINK1
SNCA
UCHL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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