Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Somatic molecular changes and histo-pathological features of colorectal cancer in Tunisia.

World journal of gastroenterology - 28 Aug 2013

Aissi Sana, Buisine Marie Pierre, Zerimech Farid, Kourda Nadia, Moussa Amel, Manai Mohamed, Porchet Nicole

Abstract excerpt

AIM: To determine correlations between family history, clinical features and mutational status of genes involved in the progression of colorectal cancer (CRC). METHODS: Histo-pathological features and molecular changes [KRAS, BRAF and CTNNB1 genes mutations, microsatellite instability (MSI) phenotype, expression of mismatch repair (MMR) and mucin (MUC) 5AC proteins, mutation and expression analysis of TP53, MLH1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta Catenin
Share to Chi-Square Distribution

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mismatch Repair

Share to Microsatellite Instability

Share to Mucin 5AC

Share to MutL Protein Homolog 1

Share to ras Proteins

Share to Tunisia

Source

Open in PubMed Open full text

Identifiers

PMID: 23983431
DOI: 10.3748/wjg.v19.i32.5286
PMCID: PMC3752562

Genes

KRAS
BRAF
CTNNB1
MLH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Somatic molecular changes and histo-pathological features of colorectal cancer in Tunisia.PMID 23983431Read ↗

Lynch syndrome in Tunisia: first description of clinical features and germline mutations.Semantic proximity Read ↗

Epigenetics could explain some Moroccan population colorectal cancers peculiarities: microsatellite instability pathway exploration.Semantic proximity Read ↗

Identification of novel pathogenic MSH2 mutation and new DNA repair genes variants: investigation of a Tunisian Lynch syndrome family with discordant twinsSemantic proximity Read ↗

TP53 mutations in colorectal cancer from Tunisia: relationships with site of tumor origin, microsatellite instability and KRAS mutations.Semantic proximity Read ↗

Studying the Impact of Tp53 Mutations on Colorectal Cancer Pathogenesis and Therapeutic Response in a Tunisian PopulationSemantic proximity Read ↗

Distinct Genetic and Epigenetic Signatures of Colorectal Cancers According to Ethnic OriginSemantic proximity Read ↗

Differing DNA methylation patterns and gene mutation frequencies in colorectal carcinomas from Middle Eastern countries.Semantic proximity Read ↗

Implication of K-ras and p53 in colorectal cancer carcinogenesis in Tunisian population cohort.Semantic proximity Read ↗

Genetic and epigenetic characteristics of patients with colorectal cancer from Uruguay.Semantic proximity Read ↗

Western influenced lifestyle and Kv2.1 association as predicted biomarkers for Tunisian colorectal cancer.Semantic proximity Read ↗

Contrasting molecular pathology of colorectal carcinoma in Egyptian and Western patientsSemantic proximity Read ↗

Clinicopathological characteristics and mutational profile of KRAS and NRAS in Tunisian patients with sporadic colorectal cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.