Association of MTHFR, MTRR and RAD54L Gene Variations with Meningioma and Correlation with Tumor's Histopathological Characteristics on Turkish Cohort.

doi:10.5137/1019-5149.JTN.33347-20.2

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Back to search

Article

Association of MTHFR, MTRR and RAD54L Gene Variations with Meningioma and Correlation with Tumor's Histopathological Characteristics on Turkish Cohort.

Turkish neurosurgery - 1 Jan 2021

Avsar Timucin, Mohiyuddin Rashid, Calis Seyma, Yapicier Ozlem, Kilic Turker

Abstract excerpt

AIM: To elucidate the association of the MTHFR, MTRR, and RAD54L gene variations with meningioma in Turkish cohort. MATERIAL AND METHODS: DNAs were isolated from 87 retrospective meningioma samples. The MTHFR, MTRR, and RAD54L gene hotspot regions were amplified with specific primers via polymerase chain reaction (PCR), and next-generation sequencing (NGS) was performed. All the detected variations and...

Topics

Adult
Aged
Case-Control Studies
Cohort Studies
DNA Helicases
DNA-Binding Proteins
Female
Ferredoxin-NADP Reductase
Gene Frequency
Genetic Association Studies
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Male

Meningeal Neoplasms

Meningioma

Methylenetetrahydrofolate Reductase (NADPH2)

Middle Aged

Polymorphism, Single Nucleotide

Source

Open in PubMed

Identifiers

PMID: 34169999
DOI: 10.5137/1019-5149.JTN.33347-20.2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of MTHFR, MTRR and RAD54L Gene Variations with Meningioma and Correlation with Tumor's Histopathological Characteristics on Turkish Cohort.PMID 34169999Read ↗

5,10-Methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTRR), and methionine synthase reductase (MTR) gene polymorphisms and adult meningioma risk.Semantic proximity Read ↗

The role of folate metabolism-related gene polymorphisms in the development of meningiomas.Semantic proximity Read ↗

Association study on MTHFR polymorphisms and meningioma in northern China.Semantic proximity Read ↗

Comprehensive analysis of DNA repair gene variants and risk of meningioma.Semantic proximity Read ↗

Functional polymorphisms in folate metabolism genes influence the risk of meningioma and glioma.Semantic proximity Read ↗

Genome-wide association study on meningioma risk in Japan: a multicenter prospective study.Semantic proximity Read ↗

[Pathological Diagnosis and Genetic Alterations of Meningioma].Semantic proximity Read ↗

Polymorphisms in DNA repair genes and risk of glioma and meningioma.Semantic proximity Read ↗

Association of the MTHFR C677T polymorphism with primary brain tumor risk.Semantic proximity Read ↗

Pathology and Molecular Genetics of Meningioma: Recent AdvancesSemantic proximity Read ↗

DNA repair gene polymorphisms and risk of adult meningioma, glioma, and acoustic neuroma.Semantic proximity Read ↗

MTHFR act as a potential cancer biomarker in immune checkpoints blockades, heterogeneity, tumor microenvironment and immune infiltrationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.