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A rapid and robust selection procedure for generating drug-selectable marker-free recombinant malaria parasites

23 Apr 2014

Abstract excerpt

Experimental genetics have been widely used to explore the biology of the malaria parasites. The rodent parasites Plasmodium berghei and less frequently P. yoelii are commonly utilised, as their complete life cycle can be reproduced in the laboratory and because they are genetically tractable via homologous recombination. However, due to the limited number of drug-selectable markers, multiple modifications of the...

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PMID: 24755823
DOI: 10.1038/srep04760

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