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Article

Initiation of metastatic breast carcinoma by targeting of the ductal epithelium with adenovirus-cre: a novel transgenic mouse model of breast cancer.

Journal of visualized experiments : JoVE - 26 Mar 2014

Rutkowski Melanie R, Allegrezza Michael J, Svoronos Nikolaos, Tesone Amelia J, Stephen Tom L, Perales-Puchalt Alfredo, Nguyen Jenny, Zhang Paul J, Fiering Steven N, Tchou Julia, Conejo-Garcia Jose R

Abstract excerpt

Breast cancer is a heterogeneous disease involving complex cellular interactions between the developing tumor and immune system, eventually resulting in exponential tumor growth and metastasis to distal tissues and the collapse of anti-tumor immunity. Many useful animal models exist to study breast cancer, but none completely recapitulate the disease progression that occurs in humans. In order to gain a better...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24748051
DOI: 10.3791/51171
PMCID: PMC4027029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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