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Mouse Mammary Tumor Virus Molecular Biology and Oncogenesis

23 Sept 2010

Abstract excerpt

Mouse mammary tumor virus (MMTV), which was discovered as a milk-transmitted, infectious cancer-inducing agent in the 1930s, has been used since that time as an animal model for the study of human breast cancer. Like other complex retroviruses, MMTV encodes a number of accessory proteins that both facilitate infection and affect host immune response. In vivo, the virus predominantly infects lymphocytes and...

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PMID: 21274409
DOI: 10.3390/v2092000

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