Article
Unusual polymorphisms in human immunodeficiency virus type 1 associated with nonprogressive infection.
Journal of virology - 1 May 2000
Alexander L, Weiskopf E, Greenough T C, Gaddis N C, Auerbach M R, Malim M H, O'Brien S J, Walker B D, Sullivan J L, Desrosiers R C
Abstract excerpt
Factors accounting for long-term nonprogression may include infection with an attenuated strain of human immunodeficiency virus type 1 (HIV-1), genetic polymorphisms in the host, and virus-specific immune responses. In this study, we examined eight individuals with nonprogressing or slowly progressing HIV-1 infection, none of whom were homozygous for host-specific polymorphisms (CCR5-Delta32, CCR2-64I, and...
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