Article
TERT promoter mutations in renal cell carcinomas and upper tract urothelial carcinomas.
Oncotarget - 15 Apr 2014
Wang Kun, Liu Tiantian, Liu Li, Liu Jikai, Liu Cheng, Wang Chang, Ge Nan, Ren Hongbo, Yan Keqiang, Hu Sanyuan, Björkholm Magnus, Fan Yidong, Xu Dawei
Abstract excerpt
TERT promoter mutations are identified in many malignancies including bladder cancer (BC) and upper tract urothelial carcinoma (UTUC). In contrast, no mutations were found in renal cell carcinoma (RCC) as reported in a recent study. Because the mutant TERT promoter in urine DNA was recently tested as a marker for BC, it is important to ascertain whether these mutations are truly absent in RCCs. Here we determined...
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