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Unaltered striatal dopamine release levels in young Parkin knockout, Pink1 knockout, DJ-1 knockout and LRRK2 R1441G transgenic mice.

PloS one - 1 Jan 2014

Sanchez Gonzalo, Varaschin Rafael K, Büeler Hansruedi, Marcogliese Paul C, Park David S, Trudeau Louis-Eric

Abstract excerpt

Parkinson's disease (PD) is one of the most prevalent neurodegenerative brain diseases; it is accompanied by extensive loss of dopamine (DA) neurons of the substantia nigra that project to the putamen, leading to impaired motor functions. Several genes have been associated with hereditary forms of the disease and transgenic mice have been developed by a number of groups to produce animal models of PD and to...

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PMID: 24733019
DOI: 10.1371/journal.pone.0094826
PMCID: PMC3986353

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Unaltered striatal dopamine release levels in young Parkin knockout, Pink1 knockout, DJ-1 knockout and LRRK2 R1441G transgenic mice.PMID 24733019Read ↗

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