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Effects in the use of a genetically engineered strain of<i>Lactococcus lactis</i>delivering in situ IL-10 as a therapy to treat low-grade colon inflammation

14 Apr 2014

Abstract excerpt

Irritable bowel syndrome (IBS) is a gastrointestinal disorder characterized by chronic abdominal pain, discomfort, and bloating. Interestingly, there is now evidence of the presence of a low-grade inflammatory status in many IBS patients, including histopathological and mucosal cytokine levels in the colon, as well as the presence of IBS-like symptoms in quiescent inflammatory bowel disease (IBD). The use of a...

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PMID: 24732667
DOI: 10.4161/hv.28549

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