Evidence from comparative genomic analyses indicating that Lactobacillus -mediated irritable bowel syndrome alleviation is mediated by conjugated linoleic acid synthesis

Abstract excerpt

Irritable bowel syndrome (IBS) is a chronic intestinal disorder accompanied by low-grade inflammation, visceral hypersensitivity, and gut microbiota dysbiosis. Several studies have indicated that Lactobacillus supplementation can help to alleviate IBS symptoms and that these effects are strain-specific. Therefore, this study aimed to investigate the key physiological characteristics and functional genes...

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