Article
QnrS1 structure-activity relationships.
The Journal of antimicrobial chemotherapy - 1 Aug 2014
Tavío María M, Jacoby George A, Hooper David C
Abstract excerpt
OBJECTIVES: Loop B is important for low-level quinolone resistance conferred by Qnr proteins. The role of individual amino acids within QnrS1 loop B in quinolone resistance and gyrase protection was assessed. METHODS: qnrS1 and 11 qnrS1 alleles with site-directed Ala mutations in loop B were expr...
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