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Article

Impact of mutations in DNA gyrase genes on quinolone resistance in Campylobacter jejuni.

Drug testing and analysis - 1 Oct 2016

Changkwanyeun Ruchirada, Yamaguchi Tomoyuki, Kongsoi Siriporn, Changkaew Kanjana, Yokoyama Kazumasa, Kim Hyun, Suthienkul Orasa, Usui Masaru, Tamura Yutaka, Nakajima Chie, Suzuki Yasuhiko

Abstract excerpt

Amino acid substitutions providing quinolone resistance to Campyloabcter jejuni have been found in the quinolone resistance-determining region of protein DNA gyrase subunit A (GyrA), with the highest frequency at position 86 followed by position 90. In this study, wild-type and mutant recombinant DNA gyrase subunits were expressed in Escherichia coli and purified using Ni-NTA agarose column chromatography....

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Identifiers

PMID: 26857529
DOI: 10.1002/dta.1937

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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