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Article

Flow cytometry test to screen for HLA-B*58:01-associated allopurinol hypersensitivity.

Clinical rheumatology - 1 Jun 2014

Scarsi Mirko, Bosio Carla, Coccoli Silvia, Barucco Amilcare, Tavelli Giovanna, Airò Paolo

Abstract excerpt

A strong association between the human leucocyte antigen (HLA)-B*58:01 allele and allopurinol-associated severe cutaneous adverse reactions (SCAR) has been reported. A screening for HLA-B*58:01 before allopurinol has been suggested in guidelines for management of gout. HLA-B*58:01 screening is ge...

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Identifiers

PMID: 24728879
DOI: 10.1007/s10067-014-2605-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24728879-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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