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Article

An effective strategy to prevent allopurinol-induced hypersensitivity by HLA typing.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Oct 2015

Jung Jae-Woo, Kim Dong-Ki, Park Heung-Woo, Oh Kook-Hwan, Joo Kwon-Wook, Kim Yon-Su, Ahn Curie, Lee Kyung Wha, Cho Sang-Heon, Min Kyung-Up, Kang Hye-Ryun

Abstract excerpt

PURPOSE: This study was conducted to evaluate the usefulness of human leukocyte antigen (HLA) typing in preventing allopurinol-induced severe cutaneous adverse reactions (SCARs) through the application of an allopurinol tolerance induction protocol or prescription of other alternative medications in high-risk patients. METHODS: HLA typing was performed in patients with chronic renal insufficiency who needed...

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Share to Allopurinol
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25634024
DOI: 10.1038/gim.2014.195

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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