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Article

Rapid screening for the detection of HLA‐B57 and HLA‐B58 in prevention of drug hypersensitivity

19 Apr 2011

Abstract excerpt

HLA-B57 and HLA-B58 are major histocompatibility class (MHC)-I allotypes that are potentially predictive of important clinical immune phenotypes. HLA-B*5701 is strongly associated with hypersensitivity to the HIV drug abacavir, liver toxicity from the antibiotic flucloxacillin and is a marker for slow progression of HIV AIDS. HLA-B*5801 is associated with hypersensitivity to allopurinol used to treat...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21501118
DOI: 10.1111/j.1399-0039.2011.01649.x

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Rapid screening for the detection of HLA‐B57 and HLA‐B58 in prevention of drug hypersensitivityPMID 21501118Read ↗

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Clinical pharmacogenetics implementation consortium guidelines for HLA-B genotype and abacavir dosing.Semantic proximity Read ↗

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