Article
The immunoglobulin gene repertoire of low-count chronic lymphocytic leukemia (CLL)-like monoclonal B lymphocytosis is different from CLL: diagnostic implications for clinical monitoring.
Blood - 2 Jul 2009
Dagklis Antonis, Fazi Claudia, Sala Cinzia, Cantarelli Valeria, Scielzo Cristina, Massacane Roberto, Toniolo Daniela, Caligaris-Cappio Federico, Stamatopoulos Kostas, Ghia Paolo
Abstract excerpt
In the revised National Cancer Institute Working Group (NCI-WG)/International Workshop on Chronic Lymphocytic Leukemia (IWCLL) guidelines for CLL, CLL-like monoclonal B lymphocytosis (MBL) is defined as the presence of less than 5 x 10(9)/L B lymphocytes in the peripheral blood. However, the concentration of MBL in the blood is extremely variable. MBL in subjects with lymphocytosis require treatment at a rate of...
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