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Genetic and environmental origins of hypospadias.

Current opinion in endocrinology, diabetes, and obesity - 1 Jun 2014

Thorup Jorgen, Nordenskjöld Agneta, Hutson John M

Abstract excerpt

PURPOSE OF REVIEW: The purpose of this study was to review and comment on recent original presentations dealing with genetic and environmental factors in the cause of hypospadias. RECENT FINDINGS: The heritability is definitely high and having an affected family member is the highest identified risk factor so far. Many candidate genes and polymorphisms have been suggested for hypospadias. Some associations with...

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Androgens
Chorionic Gonadotropin
Environmental Pollutants
Estrogen Receptor alpha
Gene-Environment Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Maternal Exposure

Prenatal Exposure Delayed Effects

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PMID: 24722170
DOI: 10.1097/MED.0000000000000063

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