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Article

Genetic polymorphisms of dsRNA ligating pattern recognition receptors TLR3, MDA5, and RIG-I. Association with systemic lupus erythematosus and clinical phenotypes.

Rheumatology international - 1 Oct 2014

Enevold C, Kjær L, Nielsen C H, Voss A, Jacobsen R S, Hermansen M L F, Redder L, Oturai A B, Jensen P E, Bendtzen K, Jacobsen S

Abstract excerpt

This study aimed to demonstrate possible associations between genetic polymorphisms in Toll-like receptor 3, interferon induced with helicase C domain 1 (IFIH1) and DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 and systemic lupus erythematosus (SLE), including the phenotypes lupus nephritis and malar rash, as well as the presence of autoantibodies against nucleic acid-containing complexes. Genotyping was carried out...

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Share to DEAD Box Protein 58
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Interferon-Induced Helicase, IFIH1

Share to Lupus Erythematosus, Systemic

Share to Receptors, Immunologic

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Source

Identifiers

PMID: 24719229
DOI: 10.1007/s00296-014-3012-4

Genes

IFIH1
TLR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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