Interferon-induced helicase (IFIH1) polymorphism with systemic lupus erythematosus and dermatomyositis/polymyositis.

doi:10.1007/s10165-010-0311-9

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Article

Interferon-induced helicase (IFIH1) polymorphism with systemic lupus erythematosus and dermatomyositis/polymyositis.

Modern rheumatology - 1 Oct 2010

Gono Takahisa, Kawaguchi Yasushi, Sugiura Tomoko, Furuya Takefumi, Kawamoto Manabu, Hanaoka Masanori, Yamanaka Hisashi

Abstract excerpt

The aim of the present study was to evaluate whether the interferon-induced helicase (IFIH1) Ala946Thr (rs1990760 A>G) polymorphism is associated with susceptibility to systemic lupus erythematosus (SLE) and dermatomyositis (DM) or polymyositis (PM) in the Japanese population. The study population consisted of 243 SLE patients, 125 DM/PM patients, and 268 healthy controls from Japan. A Taqman single nucleotide...

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PMID: 20467774
DOI: 10.1007/s10165-010-0311-9

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IFIH1

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