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Article

Oncofetal Protein IMP3, a New Cancer Biomarker

8 Apr 2014

Abstract excerpt

IMP3 is a member of a family of RNA-binding proteins that consists of IMP1, IMP2 and IMP3. These proteins contain 2 RNA recognition motifs and 4 K-homology domains that allow them to bind RNAs strongly and specifically. IMP3 is an oncofetal protein involved in embryogenesis and its expression is associated with a number of malignant neoplasms. IMP3 is associated with aggressive and advanced cancers and is...

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PMID: 24713990
DOI: 10.1097/pap.0000000000000021

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Related research

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Research trail→

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Oncofetal Protein IMP3, a New Cancer BiomarkerPMID 24713990Read ↗

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RIOK2 drives glioblastoma cell proliferation by modulating MYC through the RNA-binding protein IMP3Semantic proximity Read ↗

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The RNA-binding Protein IMP-3 Is a Translational Activator of Insulin-like Growth Factor II Leader-3 mRNA during Proliferation of Human K562 Leukemia CellsSemantic proximity Read ↗

RNA-Binding Motif Protein 3 as a Therapeutic and Prognostic Target for Drug DiscoverySemantic proximity Read ↗

IMP3, a proposed novel basal phenotype marker, is commonly overexpressed in adenoid cystic carcinomas but not in apocrine carcinomas of the breast.Semantic proximity Read ↗

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