Article
IMP3, a proposed novel basal phenotype marker, is commonly overexpressed in adenoid cystic carcinomas but not in apocrine carcinomas of the breast.
Applied immunohistochemistry & molecular morphology : AIMM - 1 Oct 2011
Vranic Semir, Gurjeva Olga, Frkovic-Grazio Snjezana, Palazzo Juan, Tawfik Ossama, Gatalica Zoran
Abstract excerpt
Insulin-like growth factor-II mRNA-binding protein 3 (IMP3) is a member of the insulin-like growth factor-II signaling pathway, and has recently been described as a biomarker of basal-like breast carcinomas. This study explored IMP3 expression in adenoid cystic carcinomas of the breast, a special type of basal-like, triple-negative (estrogen receptor/progesterone receptor/human epidermal growth factor receptor...
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