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The oncofetal protein IMP1 regulates the transcriptomic landscape to drive early events in pancreatic cancer progression and growth

2024-07-02

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background & Aims</h4> Pancreatic ductal adenocarcinoma (PDAC) has a dismal 5-year survival rate of 12% - the lowest of all malignancies. This is partially due to late diagnosis, as early stages of the disease, including the process of acinar to ductal metaplasia (ADM) are not presently detectable. Insulin-like growth factor 2 mRNA binding protein (IMP)1 is an oncofetal protein implicated i...

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Literature Corpus work
5092b4b2-3538-5d85-91a2-10187efb3c85
DOI
10.1101/2024.06.28.601273
Open publication

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The oncofetal protein IMP1 regulates the transcriptomic landscape to drive early events in pancreatic cancer progression and growthDOI 10.1101/2024.06.28.601273
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