Article
The oncofetal protein IMP3: a novel grading tool and predictor of poor clinical outcome in human gliomas.
BioMed research international - 1 Jan 2015
Del Gobbo Alessandro, Vaira Valentina, Ferrari Lucia, Patriarca Carlo, Di Cristofori Andrea, Ricca Dario, Caroli Manuela, Rampini Paolo, Bosari Silvano, Ferrero Stefano
Abstract excerpt
Morphologic criteria illustrated in WHO guidelines are the most significant prognostic factor in human gliomas, but novel biomarkers are needed to identify patients with a poorer outcome. The present study examined the expression of the oncofetal protein IMP3 in a series of 135 patients affected by high-grade (grade III and IV) gliomas, correlating the results with proliferative activity, molecular parameters,...
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