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Article

Expression profile and in vitro blockade of programmed death-1 in human papillomavirus-negative head and neck squamous cell carcinoma.

Head & neck - 1 Aug 2015

Malm Ian-James, Bruno Tullia C, Fu Juan, Zeng Qi, Taube Janis M, Westra William, Pardoll Drew, Drake Charles G, Kim Young J

Abstract excerpt

BACKGROUND: Treatment with a blocking programmed death-1 (αPD-1) antibody recently showed clinical efficacy for various tumor types. In this study, we characterized the expression profile of PD-1/programmed death-ligand-1 (PD-L1) and the potential of PD-1 blockade in human papillomavirus (HPV)-negative head and neck squamous cell carcinoma (HNSCC). METHODS: Lymphocytes from peripheral blood, draining lymph nodes,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24710745
DOI: 10.1002/hed.23706
PMCID: PMC4390546

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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