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Heterogeneity of PD-L1 expression on tumor cells and tumor-infiltrating immune cells between the primary tumor and matched lymph node metastases in head and neck squamous cell carcinomas

2024-12-17

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> The role of immune checkpoint inhibition in treating head and neck squamous cell carcinoma (HNSCC) is expanding, yet response rates to PD-L1 therapy remain inconsistent and generally poor. Although several studies have examined heterogeneous intratumoral PD-L1 expression, the disparity in response to PD-L1 therapy between primary tumors and their associated lymp...

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Literature Corpus work
2896543d-a3ab-5913-a4bc-0b4146bb1991
DOI
10.21203/rs.3.rs-5390534/v1
Open publication

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Heterogeneity of PD-L1 expression on tumor cells and tumor-infiltrating immune cells between the primary tumor and matched lymph node metastases in head and neck squamous cell carcinomasDOI 10.21203/rs.3.rs-5390534/v1
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