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Article

Analysis of Immunological Characteristics and Genomic Alterations in HPV-Positive Oropharyngeal Squamous Cell Carcinoma Based on PD-L1 Expression.

Frontiers in immunology - 1 Jan 2021

Xu Sheng-Ming, Shi Chao-Ji, Xia Rong-Hui, Wang Li-Zhen, Tian Zhen, Ye Wei-Min, Liu Liu, Liu Shu-Li, Zhang Chun-Ye, Hu Yu-Hua, Zhou Rong, Han Yong, Wang Yu, Zhang Zhi-Yuan, Li Jiang

Abstract excerpt

Programmed death-ligand 1 (PD-L1) expression has been approved as an immune checkpoint inhibitor (ICI) response predictive biomarker; however, the clinicopathological and molecular features of HPV-positive oropharyngeal squamous cell carcinoma [HPV(+)OPSCC] based on PD-L1 expression are not well studied. We aimed to characterize clinicopathological, tumor immune microenvironmental, and molecular features of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35145511
DOI: 10.3389/fimmu.2021.798424
PMCID: PMC8821172

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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