Article
An elite controller of picornavirus infection targets an epitope that is resistant to immune escape.
PloS one - 1 Jan 2014
Bell Michael P, Renner Danielle N, Johnson Aaron J, Pavelko Kevin D
Abstract excerpt
The emergence of novel viral pathogens can lead to devastating consequences in the infected population. However, on occasion, rare hyper-responsive elite controllers are able to mount a protective primary response to infection and clear the new pathogen. Factors distinguishing elite controllers from other members of the population are not completely understood. We have been using Theiler's murine...
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