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Article

Whole-genome analysis of a patient with early-stage small-cell lung cancer.

The pharmacogenomics journal - 1 Dec 2014

Han J-Y, Lee Y-S, Kim B C, Lee G K, Lee S, Kim E-H, Kim H-M, Bhak J

Abstract excerpt

We performed whole-genome sequencing (WGS) of a case of early-stage small-cell lung cancer (SCLC) to analyze the genomic features. WGS revealed a lot of single-nucleotide variations (SNVs), small insertion/deletions and chromosomal abnormality. Chromosomes 4p, 5q, 13q, 15q, 17p and 22q contained many block deletions. Especially, copy loss was observed in tumor suppressor genes RB1 and TP53, and copy gain in...

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Identifiers

PMID: 24709692
DOI: 10.1038/tpj.2014.17

Genes

CREBBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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