Article
Genetic Mutation Analysis in Small Cell Lung Cancer by a Novel NGS-Based Targeted Resequencing Gene Panel and Relation with Clinical Features.
BioMed research international - 1 Jan 2021
Jin Wang, Lei Zhao, Xu Sun, Fachen Zhou, Yixiang Zhang, Shilei Zhao, Tao Guo, Zhe Sun, Fengzhou Li, Su Wen-Hui, Chundong Gu
Abstract excerpt
BACKGROUND: Small cell lung cancer (SCLC) is an aggressive and invasive malignancy that presents at advanced clinical stage with no more effective treatments. Development of a method for its early detection would be useful, also new therapeutic target need to be discovered; however, there is a lack of information about its oncogenic driver gene mutations. OBJECTIVES: We aim to identify the SCLC-related genomic...
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