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Targeted next-generation sequencing for cancer-associated gene mutation and copy number detection in 206 patients with non-small-cell lung cancer.

Bioengineered - 1 Dec 2021

Zheng Songbai, Wang Xiaodan, Fu Ying, Li Beibei, Xu Jianhua, Wang Haifang, Huang Zhen, Xu Hui, Qiu Yurong, Shi Yaozhou, Li Kui

Abstract excerpt

The knowledge of genetic variation in Chinese patients with non-small-cell lung cancer (NSCLC) is still limited. We aimed to profile this genetic variation in 206 Chinese patients with NSCLC using next-generation sequencing. Tumor tissues or whole-blood samples were collected and subjected to whole-exome targeted next-generation sequencing, which included 565 tumor-associated genes, for somatic gene mutation...

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Identifiers

PMID: 33629637
DOI: 10.1080/21655979.2021.1890382
PMCID: PMC8291840

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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