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Article

Recent progress in mapping the emerging landscape of the small-cell lung cancer genome.

Experimental & molecular medicine - 12 Dec 2019

Kim Kee-Beom, Dunn Colin T, Park Kwon-Sik

Abstract excerpt

Small-cell lung cancer (SCLC) remains the deadliest of all the lung cancer types. Its high mortality is largely attributed to the invariable development of resistance to standard chemo/radiotherapies, which have remained unchanged for the past 30 years, underscoring the need for new therapeutic approaches. The discovery of molecular targets for chemoprevention and treatment has been hampered by the poor...

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Identifiers

PMID: 31827074
DOI: 10.1038/s12276-019-0349-5
PMCID: PMC6906379

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