Article
Genetic control of ductal morphology, estrogen-induced ductal growth, and gene expression in female mouse mammary gland.
Endocrinology - 1 Aug 2014
Wall Emma H, Case Laure K, Hewitt Sylvia C, Nguyen-Vu Trang, Candelaria Nicholes R, Teuscher Cory, Lin Chin-Yo
Abstract excerpt
The uterotropic response of the uterus to 17β-estradiol (E2) is genetically controlled, with marked variation observed depending on the mouse strain studied. Previous genetic studies from our laboratory using inbred mice that are high (C57BL6/J; B6) or low (C3H/HeJ; C3H) responders to E2 led to the identification of quantitative trait loci (QTL) associated with phenotypic variation in uterine growth and leukocyte...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
