Article
Interacting quantitative trait loci control phenotypic variation in murine estradiol-regulated responses.
Endocrinology - 1 Feb 1999
Roper R J, Griffith J S, Lyttle C R, Doerge R W, McNabb A W, Broadbent R E, Teuscher C
Abstract excerpt
The steroid hormone estradiol (E2) elicits a spectrum of systemic and uterotropic responses in vivo. For example, E2 treatment of ovariectomized adult and sexually immature rodents leads to uterine leukocytic infiltration, cell proliferation, and organ growth. E2-regulated growth is also associat...
Topics
- Animals
- Chromosome Mapping
- Chromosomes, Human, Pair 10
- Chromosomes, Human, Pair 11
- Chromosomes, Human, Pair 5
- Estradiol
- Female
- Genetic Variation
- Humans
- Leukocytes
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Organ Size
- Phenotype
- Quantitative Trait, Heritable
- Uterus