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Article

Patterns of cell signaling pathway activation that characterize mammary development.

Development (Cambridge, England) - 1 Aug 2008

Andrechek Eran R, Mori Seiichi, Rempel Rachel E, Chang Jeffrey T, Nevins Joseph R

Abstract excerpt

Previous work has detailed the histological and biochemical changes associated with mammary development and remodeling. We have now made use of gene expression profiling, and in particular of the previously described signatures of cell signaling pathway activation, to explore the events associated with mammary gland development. We find that there is elevated E2F-specific pathway activity prior to lactation and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18550711
DOI: 10.1242/dev.019018
PMCID: PMC3615553

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MYC
SRC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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