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Article

Synthesis and Propagation of Complement C3 by Microglia/Monocytes in the Aging Retina

4 Apr 2014

Abstract excerpt

INTRODUCTION: Complement activation is thought to contribute to the pathogenesis of age-related macular degeneration (AMD), which may be mediated in part by para-inflammatory processes. We aimed to investigate the expression and localization of C3, a crucial component of the complement system, in the retina during the course of aging. METHODS: SD rats were born and reared in low-light conditions, and euthanized...

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PMID: 24705166
DOI: 10.1371/journal.pone.0093343

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