Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Targeted exogenous EGFP gene editing in caprine fetus fibroblasts by zinc-finger nucleases].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology - 1 Nov 2013

Yuan Yuguo, Yu Baoli, Song Shaozheng, Zhou Feng, Zhang Liqing, Gu Yingying, Yu Minghui, Cheng Yong

Abstract excerpt

Gene knockout by ZFNs (zinc-finger nucleases) is efficient and specific, and successfully applied in more than 10 organisms. Currently, it is unclear whether this technology can be used for knocking-out enhanced green fluorescent protein (EGFP) gene in transgenic goats. Here we constructed and used ZFN-coding plasmids to produce genetic knockouts in the cells of cloned fetus produced from donor cells by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cloning, Organism
Share to Electrophoresis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Endonucleases

Share to Gene Knockout Techniques

Share to Gene Targeting

Share to Zinc Fingers

Source

Identifiers

PMID: 24701822

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Targeted exogenous EGFP gene editing in caprine fetus fibroblasts by zinc-finger nucleases].PMID 24701822Read ↗

Disruption of exogenous eGFP gene using RNA-guided endonuclease in bovine transgenic somatic cells.Semantic proximity Read ↗

Generation of gene-modified goats targeting MSTN and FGF5 via zygote injection of CRISPR/Cas9 system.Semantic proximity Read ↗

Efficient gene knockout in goats using CRISPR/Cas9 system.Semantic proximity Read ↗

Intrauterine Fetal Gene Therapy: Is That the Future and Is That Future Now?Semantic proximity Read ↗

Production of Prnp-/- goats by gene targeting in adult fibroblasts.Semantic proximity Read ↗

Generation of Five Human Lactoferrin Transgenic Cloned Goats Using Fibroblast Cells and Their Methylation Status of Putative Differential Methylation Regions of IGF2R and H19 Imprinted GenesSemantic proximity Read ↗

CRISPR/Cas9-mediated specific integration of fat-1 at the goat MSTN locus.Semantic proximity Read ↗

Establishment of protocol for preparation of gene-edited bovine ear-derived fibroblasts for somatic cell nuclear transplantation.Semantic proximity Read ↗

Role of stem cells in large animal genetic engineering in the TALENs-CRISPR era.Semantic proximity Read ↗

Production of cloned goats by nuclear transfer of cumulus cells and long‐term cultured fetal fibroblast cells into abattoir‐derived oocytesSemantic proximity Read ↗

Generation of dwarf goat (Capra hircus) clones following nuclear transfer with transfected and nontransfected fetal fibroblasts and in vitro-matured oocytes.Semantic proximity Read ↗

Establishment of a cell line carrying single copy of an exogenous mutant reporter gene for assaying the biological activity of ZFNs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.