Article
Analysis of individual protein regions provides novel insights on cancer pharmacogenomics.
PLoS computational biology - 1 Jan 2015
Porta Pardo Eduard, Godzik Adam
Abstract excerpt
The promise of personalized cancer medicine cannot be fulfilled until we gain better understanding of the connections between the genomic makeup of a patient's tumor and its response to anticancer drugs. Several datasets that include both pharmacologic profiles of cancer cell lines as well as their genomic alterations have been recently developed and extensively analyzed. However, most analyses of these datasets...
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