Article
HIV-1 persistent viremia is frequently followed by episodes of low-level viremia.
Medical microbiology and immunology - 1 Jun 2017
Widera Marek, Dirks Miriam, Bleekmann Barbara, Jablonka Robert, Däumer Martin, Walter Hauke, Ehret Robert, Verheyen Jens, Esser Stefan
Abstract excerpt
After the start of antiretroviral therapy (ART), plasma HIV-RNA levels should fall below the limit of detection (LOD) within 24 weeks. Hence, the prolonged decline of HIV-RNA after ART initiation is defined as persistent viremia (PV). In this retrospective study, we analyzed factors associated with PV. Next-generation sequencing of viral RNA/DNA was performed to study viral evolution and the emergence of...
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