Article
Antiretroviral drug resistance in HIV-1-infected patients experiencing persistent low-level viremia during first-line therapy.
The Journal of infectious diseases - 15 Aug 2011
Taiwo Babafemi, Gallien Sebastien, Aga Evgenia, Ribaudo Heather, Haubrich Richard, Kuritzkes Daniel R, Eron Joseph J
Abstract excerpt
Population sequencing was performed for persons identified with persistent low-level viremia in 2 clinical trials. Persistent low-level viremia (defined as plasma HIV-1 RNA level >50 and <1000 copies/mL in at least 2 determinations over a 24-week period, after at least 24 weeks of antiretroviral therapy) was observed in 65 (5.6%) of 1158 patients at risk. New resistance mutations were detected during persistent...
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