Article
Impact of low-level-viremia on HIV-1 drug-resistance evolution among antiretroviral treated-patients.
PloS one - 1 Jan 2012
Delaugerre Constance, Gallien Sébastien, Flandre Philippe, Mathez Dominique, Amarsy Rishma, Ferret Samuel, Timsit Julie, Molina Jean-Michel, de Truchis Pierre
Abstract excerpt
BACKGROUND: Drug-resistance mutations (DRAM) are frequently selected in patients with virological failure defined as viral load (pVL) above 500 copies/ml (c/mL), but few resistance data are available at low-level viremia (LLV). Our objective was to determine the emergence and evolution of DRAM during LLV in HIV-1-infected patients while receiving antiretroviral therapy (ART). METHODS: Retrospective analysis of...
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