Article
Predicting HLA alleles from high-resolution SNP data in three Southeast Asian populations.
Human molecular genetics - 15 Aug 2014
Pillai Nisha Esakimuthu, Okada Yukinori, Saw Woei-Yuh, Ong Rick Twee-Hee, Wang Xu, Tantoso Erwin, Xu Wenting, Peterson Trevor A, Bielawny Thomas, Ali Mohammad, Tay Koon-Yong, Poh Wan-Ting, Tan Linda Wei-Lin, Koo Seok-Hwee, Lim Wei-Yen, Soong Richie, Wenk Markus, Raychaudhuri Soumya, Little Peter, Plummer Francis A, Lee Edmund J D, Chia Kee-Seng, Luo Ma, De Bakker Paul I W, Teo Yik-Ying
Abstract excerpt
The major histocompatibility complex (MHC) containing the classical human leukocyte antigen (HLA) Class I and Class II genes is among the most polymorphic and diverse regions in the human genome. Despite the clinical importance of identifying the HLA types, very few databases jointly characterize densely genotyped single nucleotide polymorphisms (SNPs) and HLA alleles in the same samples. To date, the HapMap...
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