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Article

Insulin-like growth factor 2 enhances regulatory T-cell functions and suppresses food allergy in an experimental model.

The Journal of allergy and clinical immunology - 1 Jun 2014

Yang Gui, Geng Xiao-Rui, Song Jiang-Ping, Wu Yingying, Yan Hao, Zhan Zhengke, Yang Litao, He Weiyi, Liu Zhi-Qiang, Qiu Shuqi, Liu Zhigang, Yang Ping-Chang

Abstract excerpt

BACKGROUND: The functions of regulatory T (Treg) cells are important in immunity, and the regulatory mechanisms of Treg cell activities are not fully understood yet. OBJECTIVES: We sought to investigate the role of insulin-like growth factor (IGF) 2 in the upregulation of Treg cell function. METHODS: The expression of insulin-like growth factor 2 receptor (IGF2R) on T cells was assessed by using flow cytometry....

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Identifiers

PMID: 24698315
DOI: 10.1016/j.jaci.2014.02.019

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IGF2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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