Article
Induction of Regulatory T Cells as a Novel Mechanism Underlying the Therapeutic Action of Kakkonto, a Traditional Japanese Herbal Medicine, in a Murine Food Allergy Model.
International archives of allergy and immunology - 1 Jan 2016
Yamamoto Takeshi, Fujiwara Kanae, Tsubota Yuma, Kageyama-Yahara Natsuko, Hayashi Shusaku, Kadowaki Makoto
Abstract excerpt
BACKGROUND: The number of patients with food allergy (FA) has dramatically increased. Although satisfactory drug therapies for FA are not available, we have found that kakkonto, a traditional Japanese herbal medicine, suppressed the occurrence of allergic symptoms in an FA mouse model. Thus, we investigated whether kakkonto could regulate the activation and differentiation of T cells in the colon. METHODS: BALB/c...
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